The substance has a skin conditioning effects and is additionally used for dissolving other substances in cosmetic products.
The substance has been tested with a concentration of 25%, which did not show allergenic effects. Clinical phototoxicity tests were negative , which means that the substance is not harmful to the skin when exposed to sunlight.
In 2006, the CIR Expert Panel evaluated the substance and found it to be safe to use in cosmetic products with the applied concentrations and usage .
Dibutyl Adipate may be used in products, which have been certified by Asthma-Allergy Denmark.
The substance has proven to induce fetus abnormalities in rats, which were injected with the substance  but this is not reason for concern when used in cosmetics.